Q1.What one of the following is a clinical criteria for the diagnosis of Antiphospholipid syndrome (APLA) ?

A1. Three or more consecutive miscarriages before 10 weeks of gestation,    
A2. Three or more morphologically normal fetal losses after the 10th week of gestation    
A3. Three or more preterm births after the 34th week of gestation owing to placental disease    
A4. nbsp; Three or more preterm births before the 34th week of gestation owing to placental disease.

Q2.Balanced Robertsonian translocation in one of the causes of recurrent pregnancy loss. This translocation yields a chromosome consisting of?

A1.  Most of two metacentric chromosomes,     A2.  Most of two telocentric chromosomes     A3.  Most of two submetacentric chromosomes,     A4.   Most of two acrocentric chromosomes

Q3.Which one of the following is not an inherited thrombophilia?

A1.  Deficiency of Protein     A2.  Deficiency of Protein     A3.  Antithrombin III deficiency      A4.  Antiphospholipid syndrome

Q4.The commonest uterine developmental anomaly in women with recurrent pregnancy loss is?

A1. Arcuate uterus ;   A2. Septate uterus    A3.  Unicornuate uterus    A4. Bicornuate uterus

Q5.In the investigation of couples with recurrent pregnancy loss, parental peripheral blood karyotyping is performed ?

A1. On both partners who have had recurrent pregnancy loss with an unproven diagnosis    
A2. On both partners when their products of conception reports an unbalanced structural chromosomal abnormality    
A3.  On both partners when their products of conception reports a balanced Robertsonian translocation   
A4.  On both partners when there is an unexplained stillbirth

Q6.In the initial investigation for recurrent pregnancy loss, there is a role for testing for ?

A1.  Maternal thyroid function,     A2.  b) Maternal leucocytotoxic antibodies,     A3.  Sperm aneuploidy    A4. Parental karyotype

Q7.In the management of pregnancy with previous history of RPL, which of the following is not shown to improve live birth rate ?

A1.  Regular follow-up appointments     A2.  Regular reassurance scans    A3. Progesterone supplementation    A4. Psychological support

Q8. To prevent unexplained recurrent pregnancy loss, there is strong evidence in favour of ?

A1.  Progesterone supplementation     A2.  Metformin supplementation    A3.  Human chorionic gonadotrophin supplementation    A4. Supportive care

Q9.The following treatments are recommended for treatment of Antiphospholipid syndrome (APLA) associated with recurrent pregnancy loss ?

A1.  Aspirin     A2.  Aspirin and low molecular weight heparin     A3.  Corticosteroids    A4. Intravenous immunoglobulin

Q10.In the initial assessment of male factor in recurrent pregnancy loss, it is not clinically useful to assess ?

A1.  Intake of antioxidant     A2.  Smoking     A3.  Alcohol consumption    A4. Body weight